Physostigmine (Cholinergic)
Electrostatic Potential (red = - ; blue = +)
Updated for Spring 2009
Announcements:
10/31/2008
The textbook we will be using for spring 2009:
David G. Watson. Pharmaceutical Analysis, A Textbook for Pharmacy Students and Pharmaceutical Chemists, 2nd Edition, 2005, Elsevier. ISBN: 0443074453
"Quantitative Chemical Analysis", the 6th Edition (2002) and the new 7th Edition (2007) by DC Harris will be listed as a reference book
Students Assisting Students (SAS): for those students who need assistance in Pharmaceutical Chemistry. Please check the http://medchem.rutgers.edu/sas.shtml
To
check your grades during the semester, please go to Sakai.
Instructors:
Longqin Hu, Ph.D. Course Coordinator
Course Description: The mission of the Pharmaceutical Chemistry course is to introduce students to the structure, properties, and analysis (both qualitative and quantitative) of pharmaceutical agents and metabolites as well as the fundamental techniques used for near patient testing in clinical laboratories. Topics include some of the basic concepts in medicinal chemistry as well as methods of pharmaceutical and biomedical analysis such as 1) the drug discovery and development process, 2) review of organic functional groups found in drug molecules, 3) drug-target interactions, 4) physicochemical properties related to drug action such as acid-base properties, equilibrium, and stereochemistry, 5) Chemistry of OTC inorganic drugs, 6) Effect of chemical structure on the metabolism of drug molecules, 7) Fundamentals of neurochemistry, 8) Chromatographic analysis of pharmaceutical agents, metabolites, and clinical samples, 9) Methods for identification of pharmaceutical agents and metabolites, and 10) Spectral techniques used in quantitative analysis of clinical samples.
Lecture Schedule for Spring 2009 (PDF File)